GuttaFlow 2 is a novel filling system for root canals that combines two products in one; sealer and gutta-percha in powder form with a particle size of less than. The new GuttaFlow generation. HYGENIC GuttaFlow 2 is a novel filling system for root canals that combines two products in one: gutta-percha in powder form. The aim of the present in vitro study was to evaluate the cytotoxicity of different sealers including GuttaFlow Bioseal, GuttaFlow 2, AH-Plus and MTA Fillapex on .

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This advantage in time shows during the obturation of only one to two root canals.

Morphological cell changes due to chemical toxicity of a dental material: The composition of the test materials. The task goes well beyond the accurate filling of the 3-dimensional space within the canal.

AH-Plus Dentsply, DeTrey, Konstanz, Germany contains an epoxy resin and was found to be cytotoxic due to minimal release of formaldehyde [ 45 ]. Further studies should be carried out to investigate the biological properties of GuttaFlow Bioseal in different stem cells and in vivo. Please review our privacy policy. Future studies should assess whether the bioactive glass in GuttaFlow Bioseal has a positive effect on bone tissue. The GuttaFlow also has another property that is quite useful in its sealing ability.

Click here to view the multimedia modul of GuttaFlow.

Second, tactile sensation should be used to confirm the fit of the MC. Four replicate cell cultures were exposed to each of the extract serial dilutions in three independent experiments.


Angelus Londrina, PR, Brazil. Discussion In the present study, the cytotoxicity of GuttaFlow Bioseal extracts was investigated on L murine fibroblast cells in comparison with that of other endodontic sealers for different time points. The GuttaFlow is radiopaque and a final radiograph should be taken of the completed guttafllw canal obturation Figures 9 and Bioactive glass can be produced guttadlow soluble to non-resorbable and changed the proportions of them [ 26 ].

Apoptosis was determined by enzymatic labelling of DNA strand guttavlow using the terminal deoxynucleotidyl transferase-mediated deoxyuridine triphosphate nick-end labelling TUNEL assay. Instrumentation and Drying GuttaFlow is designed for the permanent obturation of the root canal. Gutta-percha powder, polydimethylsiloxane, silicone oil, paraffin oil, platinum catalyst, zirconium dioxide, micro silver preservativecoloring.

A novel GuttaFlow sealer supports cell survival and attachment. Gutta-percha, zinc oxide, barium sulfate, polydimethylsiloxane, bioactive glass ceramic, guttaglow, platinum catalysis, color pigments, micro silver. Open in a separate window. Differences between median values were analysed by ANOVA test for comparisons among groups, with the level of significance set at 0.

It has both osteo-integrative and osteo-conductive effects and bond mechanically to bone tissue through hydroxyapatite crystals [ 27 ].

This can be done by applying GuttaFlow directly from the dispensing gun gurtaflow dipping the MC into material on a pad. GuttaFlow is flowable at room temperature and does not require the expensive equipment sold with heated gutta percha systems.

There are a few technique tips to observe for a successful GuttaFlow obturation.

HYGENIC® GuttaFlow® 2

Preparation of SBF with different content and its influence on the composition of biomimetic apatites. Initially, only a small amount of GuttaFlow is required in a canal.

When seating the MC, insert it slowly. Figure 7 The GuttaFlow dispenser can be used to backfill any additional space that may exist in the canal.


The only equipment needed for a GuttaFlow obturation is the typical triturator found in most offices. The biocompatibility of GuttaFlow Bioseal might be due to its bioactive content and its lack of resin [ 21 ].

ROEKO GuttaFlow® 2

It contains some bioactive substances, such as calcium and silicate, which the guttafliw says stimulate tissue regeneration and healing.

Figure 4 The GuttaFlow can be placed directly into the root canal using the dispensing gun and canal tip. It should be seen rising up around the canal tip.

For example, previous studies [ 4513 ] indicated that formaldehyde released from AH-Plus may be the reason for its cytotoxicity.

The cytotoxicity of MTA Fillapex may be due to its resin component such as diluting resin and natural resin. Similarly, MTA Fillapex was highly cytotoxic in the present study.

The cytotoxicity of RoekoSeal and AH plus compared during different setting periods. Also, the MC guhtaflow as a condenser of the GuttaFlow material. Salicylate resin, diluting resin, natural resin, bismuth oxide, nano particulated silica, MTA, pigments.

Cell viability was evaluated guttafolw the 3- 4, 5-dimethylthiazolyl -2, 5-diphenyltetrazolium bromide MTT assay. Slow insertion will allow any excess GuttaFlow to flow in the path of least resistance, which is coronally, out of the canal.